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第19号(2016) >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10087/10298

Title: 動物種により異なる腸管におけるヒスタミン応答
Other Titles: Histamine Responses on Gut were different by Animal Species
Authors: 本間, 知夫
伊藤, 芽依
寺島, 和哉
関, 慎太郎
ホンマ, トモオ
イトウ, メイ
テラシマ, カズヤ
セキ, シンタロウ
Homma, Tomoo
Ito, Mei
Terashima, Kazuya
Seki, Shintaro
Keywords: 腸管
収縮
ヒスタミン
マウス
モルモット
マグヌス法
Guinea pig
Mouse
Intestines
Contraction
Histamine
Issue Date: 31-Mar-2016
Abstract: In order to study about agonist/antagonist by using acetylcholine (ACh), atropine (Atr), and histamine (His) on excised small intestine, guinea pig has been generally used as experimental animal. The present study measured intestinal contraction by ACh/Atr/His on mice and discussed the possibility of replacement of experimental animal from guinea pigs to mice. Contraction by His on mice could be obtained only at the lower part of mice ileum. So, at the present, it might be not good to use mice for this experiment.
URI: http://hdl.handle.net/10087/10298
Appears in Collections:第19号(2016)

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