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第01巻 (1980) >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10087/1805

Title: Immune responses in Sarcoma 180-bearing mice
Authors: Kurashige, Satonori
Yoshida, Toshiharu
Mitsuhashi, Susumu
Issue Date: 10-Mar-1981
Publisher: 群馬大学医療技術短期大学部
Citation: 群馬大学医療技術短期大学部紀要. 1, 36-44 (1981)
Abstract: In vitro immune responsiveness of Sarcoma 180-bearing mice was studied and following results were obtained. 1) Humoral and PHA responses were kept normal level for 4 weeks and retarded at 6 weeks (advanced stage) after tumor transplantation. 2) Cellular immune response against syngeneic tumor cells was enhanced in early stage (2 weeks) and supressed in advanced stage (6 weeks) of tumor-bearing state. 3) But regression of tumor was not observed in early stage since chemotactic activity of macrophages suppressed from early stage. 4) Purine nucleoside phosphorylase (PNP) activity of spleen lymphocytes increased in early stage (2 weeks) but decreased in advanced stage (6 weeks), suggesting that PNP activity changed in accordance with the cellular immune responsiveness against syngeneic tumor cells.
URI: http://hdl.handle.net/10087/1805
ISSN: 0389-7540
Appears in Collections:第01巻 (1980)

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