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第07巻 (1986) >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10087/1904

Title: Purine Metabolic Enzymes in Lymphocytes. V. : Purine Nucleoside Phosphorylase Activity and Suppuressor Cell Activity of Sarcoma 180-bearing Mouse Spleen Cells
Other Titles: リンパ球のプリン代謝(V) : Sarcoma 180担癌マウスの脾細胞のプリンヌクレオシドホスホリラーゼ活性とサプレッサー細胞活性
Authors: Akuzawa, Yuki
Yoshida, Toshiharu
Kurashige, Satonori
Keywords: Sarcoma 180
PNP
ADA
Suppressor cell
Issue Date: 20-Feb-1987
Publisher: 群馬大学医療技術短期大学部
Citation: 群馬大学医療技術短期大学部紀要. 7, 217-221 (1987)
Abstract: Purine nucleoside phosphorylase (PNP) activity in spleen lymphocytes of Sarcoma 180-bearing mice increased from early time after S180 transplantation and reached 5 times the normal value within 8 weeks, while no significant change was observed in adenosine deaminase (ADA) activity. More than 5 times and 3 times the normal activity of PNP were found in B and T lymphocytes, respectively, in S180-bearing mice at 8 weeks after the tumor graft. The S180-bearing mouse T and B lymphocytes with high PNP activity showed suppressor activity against the concanavalin A response of normal lymphocytes. These results suggest that PNP activity in tumor-bearing mice may be related to suppressor cell activity.
URI: http://hdl.handle.net/10087/1904
ISSN: 0389-7540
Appears in Collections:第07巻 (1986)

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